Table 3.
Characteristics of high and low UPodCR groups
| Characteristic | Highest UPodCR (n=50) | Lowest UPodCR (n=50) | P Value |
|---|---|---|---|
| Mean age ± SD (yr) | 19±18 | 32±22 | <0.01 |
| Age range (yr) | 2–80 | 7–78 | |
| Men (%) | 52 | 52 | NS |
| African American race (%) | 14 | 12 | NS |
| Mean urine UProtCR | 5.2±8.2 | 0.7±1.1 | <0.01 |
| UprotCR range | 0.4–25 | 0.04–5.2 | |
| Mean eGFR (ml/min per 1.73 m2) | 91±68 | 86±51 | NS |
| eGFR range at entry (ml/min per 1.73 m2) | 13–150 | 12–150 | |
| Renal biopsy diagnosis, n (%) | 37 (74) | 34 (68) | NS |
| Progressed to ESRD requiring RRT, n (%) | 9 (18) | 0 (0) | <0.01 |
| Angiotensin II blockade, n (%) | 38 (76) | 34 (68) | NS |
| Immunosuppression, n (%) | 29 (58) | 17 (34) | NS |
| NS and/or FSGS with UprotCR >5, n (%) | 9 (18) | 0 (0) | <0.01 |
| NS and/or FSGS with UprotCR <0.18, n (%) | 0 (0) | 11 (22) | <0.01 |
| Acute GN, n (%) | 20 (40) | 0 (0) | <0.01 |
| GNs in remission (PCR < 0.18) with or without treatment | 0 (0) | 13 (26) | <0.01 |
Clinic patients ordered according to whether their average measured UPodCR was high (in the top 50) or low (in the bottom 50). Total clinic n=358. Acute GN refers to any acute GN due to postinfectious GN, HSP, SLE, vasculitis, or similar conditions. RAS blockade refers to treatment with an angiotensin-converting enzyme Inhibitor or an angiotensin II receptor blocker. Immunosuppression includes a wide range of immunosuppressive agents (see Concise Methods).