Table 3.
Variable | Incident | Prevalent | ||
---|---|---|---|---|
Coefficient (95% CI) | P Value | Coefficient (95% CI) | P Value | |
Age (per decade) | 0.001 (−0.005 to 0.008) | 0.7 | −0.004 (−0.012 to 0.004) | 0.4 |
Body mass index | −0.002a (−0.005 to −0.0001) | 0.04 | −0.0009 (−0.004 to 0.002) | 0.5 |
APD use | −0.02 (−0.06 to 0.02) | 0.3 | −0.008 (−0.04 to 0.03) | 0.7 |
Systolic BP (per 10 mmHg) | 0.005a (0.0002 to 0.009) | 0.04 | 0.001 (−0.004 to 0.007) | 0.6 |
Male sex | 0.02a (0.003 to 0.04) | 0.02 | 0.02a (0.002 to 0.05) | 0.04 |
Duration of PD | 0.08×monthb (0.03 to 0.13) | <0.001 | 0.01×yearb (0.004 to 0.02) | 0.003 |
0.02×montha (0.04 to 0.003) | ||||
Biocompatible solution use | −0.005 (−0.02 to 0.02) | 0.7 | −0.04a (−0.07 to (−0.004) | 0.03 |
Icodextrin use | 0.06b (0.03 to 0.09) | <0.001 | 0.04a (0.01 to 0.07) | 0.01 |
Average glucose concentration (per g/L) | 0.005b (0.002 to 0.007) | <0.001 | 0.005b (0.001 to 0.008) | 0.004 |
Dialysate IL-6 | 0.08b (0.06 to 0.11) | <0.001 | 0.09b (0.07 to 0.12) | <0.001 |
Dialysate TNF-α | 0.04 (−0.03 to 0.10) | 0.3 | −0.03 (−0.1 to 0.06) | 0.6 |
Dialysate IFN-γ | −0.009 (−0.04 to 0.02) | 0.6 | 0.008 (−0.03 to 0.04) | 0.6 |
Plasma IL-6 | −0.02 (−0.06 to 0.01) | 0.2 | 0.006 (−0.04 to 0.05) | 0.8 |
Plasma TNF-α | 0.02 (−0.04 to 0.09) | 0.5 | −0.05 (−0.12 to 0.02) | 0.2 |
Plasma IFN-γ | −0.009 (−0.04 to 0.02) | 0.6 | −0.02 (−0.06 to 0.03) | 0.4 |
Plasma IL-1β | 0.02 (−0.06 to 0.11) | 0.6 | 0.001 (−0.09 to 0.09) | 0.98 |
Diabetic | 0.02a (0.001 to 0.05) | 0.04 | 0.004 (−0.03 to 0.03) | 0.8 |
Comorbidity | 0.0005 (−0.01 to 0.01) | 0.9 | 0.003 (−0.01 to 0.02) | 0.7 |
Urine volume (per L) | 0.0b (0.01 to 0.04) | <0.001 | 0.02a (0.005 to 0.04) | 0.01 |
Korean | 0.08a (0.01 to 0.15) | 0.02 | 0.05 (−0.005 to 0.11) | 0.07 |
Data are presented so that coefficients represent the change in dialysate-to-plasma creatinine ratio. A total of 499 and 307 patients were in the final models for incident and prevalent patients, respectively. Cytokine coefficients are per log10 changes in concentration. CI, confidence interval.
P=0.01–0.05.
P<0.01.