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. 2013 Sep 5;24(12):2071–2080. doi: 10.1681/ASN.2013030314

Table 3.

Predictors of PSTR

Variable Incident Prevalent
Coefficient (95% CI) P Value Coefficient (95% CI) P Value
Age (per decade) 0.001 (−0.005 to 0.008) 0.7 −0.004 (−0.012 to 0.004) 0.4
Body mass index −0.002a (−0.005 to −0.0001) 0.04 −0.0009 (−0.004 to 0.002) 0.5
APD use −0.02 (−0.06 to 0.02) 0.3 −0.008 (−0.04 to 0.03) 0.7
Systolic BP (per 10 mmHg) 0.005a (0.0002 to 0.009) 0.04 0.001 (−0.004 to 0.007) 0.6
Male sex 0.02a (0.003 to 0.04) 0.02 0.02a (0.002 to 0.05) 0.04
Duration of PD 0.08×monthb (0.03 to 0.13) <0.001 0.01×yearb (0.004 to 0.02) 0.003
0.02×montha (0.04 to 0.003)
Biocompatible solution use −0.005 (−0.02 to 0.02) 0.7 −0.04a (−0.07 to (−0.004) 0.03
Icodextrin use 0.06b (0.03 to 0.09) <0.001 0.04a (0.01 to 0.07) 0.01
Average glucose concentration (per g/L) 0.005b (0.002 to 0.007) <0.001 0.005b (0.001 to 0.008) 0.004
Dialysate IL-6 0.08b (0.06 to 0.11) <0.001 0.09b (0.07 to 0.12) <0.001
Dialysate TNF-α 0.04 (−0.03 to 0.10) 0.3 −0.03 (−0.1 to 0.06) 0.6
Dialysate IFN-γ −0.009 (−0.04 to 0.02) 0.6 0.008 (−0.03 to 0.04) 0.6
Plasma IL-6 −0.02 (−0.06 to 0.01) 0.2 0.006 (−0.04 to 0.05) 0.8
Plasma TNF-α 0.02 (−0.04 to 0.09) 0.5 −0.05 (−0.12 to 0.02) 0.2
Plasma IFN-γ −0.009 (−0.04 to 0.02) 0.6 −0.02 (−0.06 to 0.03) 0.4
Plasma IL-1β 0.02 (−0.06 to 0.11) 0.6 0.001 (−0.09 to 0.09) 0.98
Diabetic 0.02a (0.001 to 0.05) 0.04 0.004 (−0.03 to 0.03) 0.8
Comorbidity 0.0005 (−0.01 to 0.01) 0.9 0.003 (−0.01 to 0.02) 0.7
Urine volume (per L) 0.0b (0.01 to 0.04) <0.001 0.02a (0.005 to 0.04) 0.01
Korean 0.08a (0.01 to 0.15) 0.02 0.05 (−0.005 to 0.11) 0.07

Data are presented so that coefficients represent the change in dialysate-to-plasma creatinine ratio. A total of 499 and 307 patients were in the final models for incident and prevalent patients, respectively. Cytokine coefficients are per log10 changes in concentration. CI, confidence interval.

a

P=0.01–0.05.

b

P<0.01.