Table 6.

Predictors of survival

Variable	Incident		Prevalent
	Hazard Ratio (95% CI)	P Value	Hazard Ratio (95% CI)	P Value
Dialysate TNF-α	0.99 (0.34 to 2.89)	0.98	0.86 (0.22 to 3.43)	0.8
Dialysate IL-6	0.93 (0.66 to 1.31)	0.7	0.96 (0.65 to 1.44)	0.9
Dialysate IFN-γ	1.18 (0.69 to 2.00)	0.5	1.20 (0.65 to 2.19)	0.6
Plasma IL-1β	0.56 (0.15 to 2.15)	0.4	0.52 (0.16 to 1.74)	0.3
Plasma TNF-α	3.39a (1.26–9.16)	0.02	2.03 (0.52 to 7.93)	0.3
Plasma IL-6	2.15b (1.22 to 3.78)	0.008	2.68b (1.28 to 5.58)	0.009
Plasma IFN-γ	0.89 (0.49 to 1.60)	0.7	1.16 (0.62 to 2.16)	0.6
Age (per yr)	1.06b (1.05 to 1.08)	<0.001	1.06b (1.04 to 1.07)	<0.001
Male sex	0.94 (0.69 to 1.29)	0.7	1.28 (0.92 to 1.78)	0.1
Comorbidity (per disease)	1.68b (1.44 to 1.96)	<0.001	1.37b (1.18 to 1.58)	<0.001
Urine volume (per L)	0.95 (0.76 to 1.19)	0.7	0.65b (0.48 to 0.87)	0.004
Duration of PD (per mo)	1.17 (0.05 to 29.16)	0.9	1.14b (1.04 to 1.24)	0.005
Albumin (per 1 g/dl)	0.94b (0.91 to 0.97)	<0.001	0.99 (0.95 to 1.03)	0.6
PSTR (per 0.1 increase in dialysate-to-plasma creatinine ratio)	1.10 (0.98 to 1.23)	0.1	1.18a (1.003 to 1.41)	0.049
Body mass index	1.01 (0.97 to 1.05)	0.6	1.01 (0.98 to 1.04)	0.6

Models stratified by center. Cytokine hazard ratios are for each 1×log₁₀ change in concentration. CI, confidence interval.

^aP=0.01–0.05.

^bP<0.01.