Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Significance of PCNA and its ubiquitination for DNA damage tolerance pathways in budding yeast. Depicted is the repurposing of PCNA from its role as a processivity factor in normal replication by Rad6-Rad18 dependent monoubiquitination or Mms2-Ubc13-Rad5 polyubiquitination for error-free or error-prone translesion synthesis (TLS) and error-free postreplication repair (PRR). (From Zhang et al. 2011; adapted, with permission, from Elsevier © 2011.)
