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. Author manuscript; available in PMC: 2013 Nov 25.
Published in final edited form as: IEEE Trans Med Imaging. 2013 Apr 5;32(9):10.1109/TMI.2013.2257177. doi: 10.1109/TMI.2013.2257177

Figure 1.

Figure 1

Simultaneous excitation and reception in MPI leads to direct feedthrough interference, which contaminates the received signal at the fundamental drive frequency. Aggressive filtering removes the direct feedthrough interference, however it also removes part of the nanoparticle signal. It is necessary to recover the lost signal to enable artifact-free MPI images. (a) Simplified block diagram of the MPI system. Excitation and reception occur simultaneously. (b) Frequency spectrum of the signal detected in the receive coil. Sinusoidal excitation leads to harmonics in the nanoparticle signal spectrum. A high-pass filter is applied to remove the fundamental feedthrough signal.