Table 1.

Patient characteristics

Variable	Cediranib + chemoradiation (n = 46)	Chemoradiation alone (n = 14)	Perfusion increased* (n = 20)	Perfusion stable/reduced* (n = 20)
Age	57 (22–74)	60 (35–70)	59 (22–74)	57 (41–67)
KPS	90 (60–100)	90 (60–100)	100 (90–100)	90 (60–100)
EOR	36 subtotal resection	10 subtotal resection	16 subtotal resection	16 subtotal resection
	10 biopsy	4 biopsy	4 biopsy	4 biopsy
Sex	14 women	8 women	8 women	5 women
	32 men	6 men	12 men	15 men
MGMT	19 methylated	2 methylated	8 methylated	7 methylated
	18 unmethylated	8 unmethylated	9 unmethylated	10 unmethylated
	9 unable to determine†	4 unable to determine†	3 unable to determine†	3 unable to determine†

EOR, extent of resection.

^*Total n = 40 patients in the phase II component of study.

^†Technical failure or insufficient tissue.