Fig. 5.

Plasma hypomethylation and CNA analyses for three representative patients suffering from breast, lung, and nasopharyngeal cancers. The inner ring and outer ring show the CNA and methylation z scores, respectively. Each dot represents a 1-Mb bin. For CNA analysis, the green, red, and gray dots represent bins with chromosome gain, loss, and normal chromosome dosage, respectively. For methylation analysis, the red and gray dots represent bins with and without hypomethylation, respectively. The distance between two parallel lines represents a z-score difference of 5.