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Impact of depleting NadE on nonreplicating Mtb. (A) Survival during starvation in PBS without atc (white symbols) or with atc (black symbols). Data are means ± SEM of five replicates. (B) Survival during hypoxia after adding atc on day 9 (black), day 16 (orange), or day 24 (purple). Dotted lines end in or start with data points for which the titer was below the limit of detection of 1 cfu/mL. Data are means ± SEM of three replicates.
