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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Curr Opin Immunol. 2013 Oct 1;25(5):10.1016/j.coi.2013.09.004. doi: 10.1016/j.coi.2013.09.004

Figure 2. E protein activity is regulated by Id proteins.

Figure 2

E protein dimers bound to DNA can activate (top) or repress gene transcription. When E proteins heterodimerize with Id proteins, DNA binding is inhibited, also blocking target gene transcription (bottom).