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. 2013 Nov 25;8(11):e82546. doi: 10.1371/journal.pone.0082546

Figure 6. Sciatic experiment muscle weight and motor neuron labeling results.

Figure 6

Tibialis anterior muscle weights demonstrated no significant differences between the NIC groups or from Crush s and Sham s groups. Transection s and Negative Control s groups showed statistically significant differences from other groups (A) (n=6 per group). Statistically significant attrition of motor neurons with axons that regenerated into the MG nerve was demonstrated in the Transection s group, compared to Sham s and Crush s groups (B) (n=6 per group). Relative percentage of axonal misdirection to the MG and sural nerves were calculated by dividing the counted cells “out”-side the reference boundaries by the “total” counts (e.g. %misdirection to sural = Di-I-out/Di-I-total x100). Transection s (n=5) injuries demonstrated the most misdirection and the same trend was found among the NIC injury groups with MG and sural nerve assessments. Average of MG and sural results shown (C) (n=6 per other groups). (*p<0.05,**p<0.001).