Table 2. Plasma levels of miRNA expression by EGFR mutation status.

MiRNA expression	Median (range)	(2-ΔΔCq)a	P value
	EGFR wild (n=48)	EGFR mutant (n=57)
miR-155	0.91(0.28-6.67)	1.12(0.29-3.18)	0.557
miR-25	1.15(0.14-11.67)	0.89(0.12-9.82)	0.339
miR-16	1.17(0.13-8.56)	0.83(0.08-11.21)	0.087
miR-133a	0.88(0.07-9.64)	1.37(0.09-10.56)	0.077
miR-19a	1.21(0.22-6.05)	1.11(0.02-12.91)	0.221
miR-19b	1.16(0.23-6.14)	1.04(0.04-9.57)	0.310
miR-20a	1.06(0.27-8.46)	1.05(0.02-8.35)	0.332
miR-20b	1.09(0.16-12.06)	0.85(0.05-11.89)	0.165
miR-629	0.92(0.16-7.01)	0.91(0.16-9.18)	0.665
miR-451	1.08(0.08-13.95)	0.90(0.02-11.40)	0.114
miR-192	0.92(0.23-9.66)	0.91(0.14-9.57)	0.295
miR-195	1.13(0.22-8.98)	0.93(0.03-14.36)	0.133
miR-122	1.11(0.26-14.47)	0.84(0.04-21.14)	0.018
miR-106b	1.01(0.17-9.79)	1.05(0.11-6.07)	0.946
miR-26b	1.09(0.13-8.47)	1.10(0.04-5.46)	0.972
miR-143	1.05(0.20-17.34)	1.07(0.04-3.70)	0.615
miR-374	1.27(0.11-10.52)	1.11(0.02-7.93)	0.528
miR-374-5p	1.11(0.08-7.98)	0.99(0.01-7.93)	0.820
miR-486-3p	1.13(0.14-8.72)	0.75(0.06-9.97)	0.093
miR-590-5p	1.06(0.06-4.15)	1.04(0.09-8.52)	0.885

a: Expression level were calculated using the 2^{- ΔΔCq} method.

miR-A_ΔCq = miR-A _{raw Cq}- miR-A_{mean Cq},

miR-A _ΔΔCq= miR-A _ΔCq- cel-miR-39 _ΔCq