Table 4. miRNA expression and survival in non-smoking female lung adenocarcinoma.
miRNAs | group | Number n =105 | HR (95% CI) | HR a (95% CI) | Log-rank P |
---|---|---|---|---|---|
miR-155 | LE | 52 | 1.00 | 1.00 | 0.533 |
HE | 53 | 1.29(0.58-2.89) | 1.38(0.61-3.13) | ||
miR-25 | LE | 53 | 1.00 | 1.00 | 0.160 |
HE | 52 | 0.55(0.23-1.29) | 0.68(0.28-1.62) | ||
miR-16 | LE | 52 | 1.00 | 1.00 | 0.184 |
HE | 53 | 0.57(0.24-1.33) | 0.61(0.26-1.47) | ||
miR-133a | LE | 52 | 1.00 | 1.00 | 0.280 |
HE | 53 | 1.57(0.69-3.62) | 1.86(0.79-4.35) | ||
miR-19a | LE | 52 | 1.00 | 1.00 | 0.040 |
HE | 53 | 0.41(0.17-0.99) | 0.41(0.17-1.00) | ||
miR-19b | LE | 52 | 1.00 | 1.00 | 0.095 |
HE | 53 | 0.49(0.21-1.16) | 0.51(0.22-1.22) | ||
miR-20a | LE | 53 | 1.00 | 1.00 | 0.218 |
HE | 52 | 0.59(0.25-1.39) | 0.68(0.28-1.63) | ||
miR-20b | LE | 52 | 1.00 | 1.00 | 0.180 |
HE | 53 | 0.56(0.24-1.32) | 0.63(0.26-1.51) | ||
miR-629 | LE | 52 | 1.00 | 1.00 | 0.218 |
HE | 53 | 0.60(0.26-1.37) | 0.61(0.27-1.39) | ||
miR-451 | LE | 52 | 1.00 | 1.00 | 0.335 |
HE | 53 | 0.67(0.29-1.53) | 0.79(0.34-1.86) | ||
miR-192 | LE | 51 | 1.00 | 1.00 | 0.093 |
HE | 54 | 0.49(0.21-1.15) | 0.55(0.23-1.31) | ||
miR-195 | LE | 53 | 1.00 | 1.00 | 0.011 |
HE | 52 | 0.30(0.11-0.80) | 0.31(0.11-0.83) | ||
miR-122 | LE | 53 | 1.00 | 1.00 | 0.012 |
HE | 52 | 0.33(0.13-0.82) | 0.34(0.13-0.88) | ||
miR-106b | LE | 53 | 1.00 | 1.00 | 0.090 |
HE | 52 | 0.49(0.21-1.14) | 0.49(0.20-1.21) | ||
miR-26b | LE | 52 | 1.00 | 1.00 | 0.831 |
HE | 53 | 0.92(0.41-2.06) | 0.98(0.41-2.31) | ||
miR-143 | LE | 53 | 1.00 | 1.00 | 0.497 |
HE | 52 | 1.32(0.59-2.99) | 1.29(0.54-3.06) | ||
miR-374 | LE | 52 | 1.00 | 1.00 | 0.892 |
HE | 53 | 1.06(0.47-2.39) | 1.03(0.44-2.43) | ||
miR-374-5p | LE | 52 | 1.00 | 1.00 | 0.887 |
HE | 53 | 0.94(0.42-2.12) | 0.92(0.39-2.18) | ||
miR-486-3p | LE | 53 | 1.00 | 1.00 | 0.096 |
HE | 52 | 0.48(0.20-1.17) | 0.55(0.23-1.36) | ||
miR-590-5p | LE | 52 | 1.00 | 1.00 | 0.052 |
HE | 53 | 0.44(0.19-1.03) | 0.43(0.18-1.02) |
LE: Low Expression; HE: High Expression. LE and HE were divided by median expression of specific miRNA.
adjusted for stage, age and treatment