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. 2013 Nov 25;8(11):e81430. doi: 10.1371/journal.pone.0081430

Figure 3. Normalized fluorescence for in vivo imaging of ICG labeled cells and ICG solution.

Figure 3

(A) Normalized fluorescence of inoculation area. Normalized fluorescence is significantly higher in the infection model (N=8) than in the inflammation model (N=8) as early as 2 hours after cellular injection (p<0.05). After injection of ICG solution, normalized fluorescence in the infection model (N=8) is significantly higher than in the inflammation model (N=8) at the 8, 12, and 24 hour time points (p<0.05). Normalized fluorescence after injection of cells was significantly higher than after injection of ICG solution from the 6 hour time point onward (p<0.05). Fluorescence intensity was normalized to the intensity at 0 hours after injection. (B) Normalized fluorescence of contralateral control area. Normalized fluorescence generally decreases throughout the study in all groups (N=8 each). All error bars represent SEM.