Table 4. Association between polymorphisms in alcohol metabolism genes and alcohol consumption (men only).
| SNP | Alcohol consumption | OR1 | 95% CI | p-value | |
| No or Occasional | Yes | ||||
| N (%) | N (%) | ||||
| ADH1B rs1229984 | 690 (74.7) | 234 (25.3) | 0.10 | ||
| G/G | 378 (54.8) | 133 (56.8) | 1.00 | ||
| G/A | 276 (40.0) | 83 (35.5) | 0.83 | (0.60–1.15) | |
| A/A | 36 (5.2) | 18 (7.7) | 1.66 | (0.89–3.08) | |
| Recessive (A/A) | 36 (5.2) | 18 (7.7) | 1.79 | (0.97–3.28) | 0.068 |
| ALDH2 rs886205 | 682 (74.7) | 231 (25.3) | 0.69 | ||
| T/T | 493 (72.3) | 164 (71.0) | 1.00 | ||
| T/C | 166 (24.3) | 62 (26.8) | 1.10 | (0.77–1.57) | |
| C/C | 23 (3.4) | 5 (2.2) | 0.72 | (0.25–2.02) | |
| Dominant (T/C-C/C) | 189 (27.7) | 67 (29.0) | 1.06 | (0.75–1.50) | 0.75 |
1
OR adjusted for age, ethnicity, religion, energy intake and physical activity.