Figure 4.
Transmission electron micrographs representative of MCF-7 cells. Confluent cells (60–70%) were treated with 6 μM of α-tomatine for 4 h. Images of transverse sections of the cells are shown. (A) Control cells, (B) α-tomatine-treated cells. The treated cells show disintegration of both the outer and nuclear membranes, but no typical morphologic signs of apoptosis.