Table 4. Summary of significant associations with disease outcomes, derived from single case-control studies.

Study	Population	Disease Outcome	Polymorphism	ORG (95% CI)
Goepfert [86]	USA	Bacterial vaginosis (pregnancy)	TLR4 1196 C>T	0.55 (0.31-0.98)
Rezazadeh[30]	Iran	Brucellosis	TLR4 896 A>G	2.66 (1.66-4.27)
Ajdary [36]	Iran	Cutaneous leishmaniasis	TLR4 896 A>G	7.22 (1.91-27.29)
			TLR4 1196 C>T	10.14 (1.90-54.16)
Bochud [38]	East Africa	Leprosy	TLR4 896 A>G	0.36 (0.22-0.60)
			TLR4 1196 C>T	0.23(0.10-0.55)
Verma [40]	India	Neurocysticercosis	TLR4 896 A>G	4.39 (2.53-7.61)
			TLR4 1196 C>T	3.13 (1.46-6.73)
Liadaki [46]	Greece	H.influenzae (tonsillitis)	TLR4 1196 C>T	0.42 (0.17-1.00)
Liadaki [46]	Greece	S.pyogenes (tonsillitis)	TLR4 896 A>G	2.93 (1.24-6.93)
			TLR4 1196 C>T	3.12 (1.36-7.13)
Bhuvanedran [47]	Malaysia	Typhoid fever	TLR4 896 A>G	2.51 (1.18-5.34)
			TLR4 1196 C>T	2.26 (1.01-5.07)
Yin [48]	China	UTI (Adults)	TLR4 896 A>G	1.98 (1.04-3.98)