Table 1.
Lesion | Base excision or binding | Lesion | Base excision or binding |
---|---|---|---|
ssAP | +++ | AP:C | + |
ssGh | +++ | Gh:C | ++ |
ssSp | +++ | Sp:C | ++ |
ss5OHC | + | 5OHC:G | − |
ss5OHU | + | 5OHU:A | − |
ssDHT | − | DHT:A | − |
ssDHU | ± | DHU:A | − |
ssU | − | U:A | − |
hairpin | − | 8oxoG:C | − |
3′flap | − | 5′flap | − |
A:A mismatch | − | A:TT loop | − |
3-Way junction | − | I:T | − |
εC:G | − | εA:T | − |
1 ssrA | − | 1 rA:T | − |
1 ssrU | − | 1 rU:A | − |
1 ssrC | − | 1 rC:G | − |
1 ssrG | − | 1 rG:C | − |
ssHmc | − | HmC:G | − |
Ss5meC | − | 5meC:G | − |
Abbreviations: 3′flap, DNA duplex with single stranded 3′ overhang; 3-way junction, replication intermediate, 5′flap, DNA duplex with single stranded 5′overhang; 5meC, 5-methylcytosine; 5OHC, 5-hydroxycytosine; 5OHU, 5-hydroxyuracil; A:TT, insertion loop; εA, 1,N6-ethenoadenine; εC, 3,NA-ethenocytosine; DHT, 5,6-dihydrothymine; DHU, 5,6-dihydroxyuracil; Gh, guanidinohydantoin; HmC, 5-hydroxymethylcytosine; I, inosine; Sp, spiroiminodihydantoin;
DNA oligo with one ribonucleotide incorporated.