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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Am J Obstet Gynecol. 2013 Aug 9;209(6):10.1016/j.ajog.2013.08.004. doi: 10.1016/j.ajog.2013.08.004

Figure 2.

Figure 2

The TGF-WNT/cytoskeleton remodeling pathway is associated with survival from OVCA, colon cancer, and leukemia. (A) TGF-WNT/cytoskeleton remodeling pathway. Thermometers indicate the directional change (upward or downward) in expression of genes associated with extra-pelvic implant samples. Numbers 1–2 at base identify the originating dataset (1 = grouped analysis, unique to NOSE versus extra-pelvic implant; 2 = individual analysis; common to ≥15 paired samples). (B–D) Kaplan-Meier curves depicting the association between the TGF-WNT/cytoskeleton remodeling-pathway PCA score (using median PCA threshold) and overall survival from OVCA (GSE9891, survival information available for 218 of the 220 samples) (B), colon cancer (GSE17538, n=177 (C), and leukemia (TCGA database, n=182 (D). Log-rank test P values indicate significance.