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CoQ10 does not diminish apoptotic effect of doxorubicin. MDA-MB-468 (A) and BT549 (B) cells were treated with CoQ10 alone, doxorubicin alone or a combination of the two. Cleaved caspase-3 levels were evaluated using immunoblotting as a measure of apoptotic activity in the cells. MDA-MB-468 cells were treated with 800nM doxorubicin; BT549 cells were treated with 3.2uM doxorubicin.
Abbreviations: CoQ10, Coenzyme Q10; dox, doxorubicin
