Fig. 5.

α₁-Adrenoceptor agonist facilitated spiking-independent glycinergic synaptic transmission in the WT HNs. A: sample traces showing the effect of PE on mIPSCs recorded in the presence of CNQX, dl-AP5, bicuculline, and 1 μM TTX, under control (top) and during 40 μM PE application (bottom). B and C: cumulative distribution of the interevent interval and amplitude curves obtained from the same neuron as in A. PE shifted the interevent interval curve (B) at left but had no significant effect on the amplitude distribution curve (C). D: bar graphs summarizing the effect of PE on mIPSCs frequency and amplitude expressed as percentage of control ± SE. **P < 0.01; n, number of neurons examined.