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Oral glucose tolerance test (OGTT) and intraperitoneal insulin tolerance test (ipITT) in the rats receiving a 7-day treatment of ANG II, ANG II + Los, C21, and C21 + PD. A: blood glucose. B: serum insulin in OGTT. C: glucose concentration in ipITT. OGTT and ipITT were performed after 16 and 4 h of fasting, respectively. *P < 0.05 and **P < 0.01, ANG II, ANG II + Los, and C21 vs. control; #P < 0.05, C21 + PD vs. C21; @P < 0.05, ANG II and C21 vs. control. n = 7/group.
