Fig. 7.

Human islets are viable after silica coating and show improved viability in culture over time. Islets were stained with CellTracker Green CMFDA (live cell, green) and PI (red). Confocal imaging reveals even distribution of a few PI-permeable cells 1 day (A) and 7 days (B) after coating. C: islet viability of encapsulated human islets is reduced on the day of encapsulation but improved 2 and 7 days after encapsulation. *P < 0.01 vs. groups of nonencapsulated islets. All data normalized to nonencapsulated human islet viability. Error bars, ±1 SE (n = 3–4 replicates per condition).