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Time- and tissue-dependent regulation of TβR-3-IR following CYP treatment. A–D: representative images of TβR-3-IR in the detrusor smooth muscle following control or CYP treatment paradigms. E: semiquantitative analyses in the detrusor smooth muscle revealed a significant suprathreshold increase following intermediate (48 h) or chronic CYP-induced cystitis. Calibration bar represents 25 μm. Values are means ± SE; n = 4/condition. **P ≤ 0.01 vs. control.
