Table 2.

Selected differentially displayed genera in the distal colonic content of WT and NHE3^−/− mice

		WT		NHE3−/−		t-Test
Phylum	Genus	Mean, %	SE	Mean, %	SE	P Value
Firmicutes	Marvinbryantia	0.51	0.07	0.02	0.01	0.000
	Anaerotruncus	0.63	0.09	0.04	0.02	0.000
	Oscillibacter	4.69	0.85	0.50	0.17	0.001
	Coprococcus	16.54	2.73	3.11	0.52	0.001
	Moryella	0.83	0.12	0.18	0.07	0.002
	Dorea	1.28	0.22	0.19	0.07	0.002
	Proteocatella	4.15	1.02	0.21	0.12	0.006
	Oribacterium	13.52	3.76	0.12	0.05	0.008
	Acetivibrio	0.37	0.10	0.03	0.02	0.009
	Lactonifactor	0.19	0.05	0.00	0.00	0.010
	Coprobacillus	0.00	0.00	0.09	0.03	0.016
	Lactobacillus	17.19	4.14	4.81	1.26	0.023
	Roseburia	2.96	0.97	0.24	0.17	0.026
	Sporacetigenium	0.03	0.02	0.72	0.26	0.026
	Acetitomaculum	0.10	0.04	0.00	0.00	0.050
	Sporobacter	0.06	0.02	0.00	0.00	0.052
	Butyricicoccus	0.10	0.04	0.01	0.01	0.058
	Butyrivibrio	0.09	0.04	0.00	0.00	0.063
	Peptococcus	0.03	0.01	0.00	0.00	0.066
	Enterococcus	0.00	0.00	0.07	0.03	0.069
	Anaerobacter	0.73	0.27	4.55	1.96	0.081
	Hespellia	0.38	0.20	0.00	0.00	0.097
Proteobacteria	Parasutterella	0.05	0.03	0.49	0.10	0.002
	Desulfovibrio	0.05	0.01	0.00	0.00	0.013
	Actinobacillus	0.00	0.00	0.06	0.03	0.056
	Bdellovibrio	0.03	0.02	0.00	0.00	0.072
	Helicobacter	4.63	1.62	18.87	7.07	0.078
	Thioreductor	0.02	0.01	2.15	1.16	0.092
Bacteroidetes	Parabacteroides	0.50	0.12	17.01	3.37	0.001
	Bacteroides	1.50	0.30	11.10	2.30	0.003
	Haliscomenobacter	0.77	0.15	0.15	0.09	0.007
	Parasegetibacter	0.13	0.04	0.01	0.01	0.016
	Anaerophaga	1.84	0.66	4.94	1.02	0.031

Genera were selected based on t-test P < 0.1 and sorted by increasing P value within each phylum. Mean and SE for each genotype is indicated (n = 4 for WT and n = 6 for NHE3^−/− mice). NHE, Na⁺/H⁺ exchange.