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Codeletion of TRPV1 and P2X3 (i.e., TPDKO) had no effect on proportions (A) or electrical activation thresholds (B) of pelvic nerve colorectal afferents. A total 116 fibers was studied from 23 C57BL/6 mice and 102 fibers from 24 TPDKO mice. musc, muscular; mucos, mucosal; M/M, muscular/mucosal; MIA, mechanically insensitive afferent.
