Responses of muscular (A), but not muscular/mucosal (B), afferents to circumferential stretch (0–170 mN, 5 mN/s) were reduced in TPDKO relative to C57BL/6 mice (F1/180 = 11.8, *P < 0.001). Insets: response thresholds were increased in muscular (t = 4.3, P < 0.001), but not muscular/mucosal, afferents. C and D: responses of muscular and muscular/mucosal afferents to stepped stretch (0.2-s rise time) did not differ between genotypes. n = number of fibers/group.