Dietary fatty acid fractional absorption vs. hydrophobicity. The mean fractional absorption of each individual fatty acid, saturated (dark shaded circle), monounsaturated (light shaded square), or polyunsaturated (open triangle), was plotted vs. its reverse-phase HPLC column retention time and micellar partition coefficient, two measures that reflect fatty acid hydrophobicity. Retention times were taken from the literature (9, 38); micellar partition coefficients were taken directly from the literature (55) or extrapolated using data from Refs. 9, 38, and 55. The line is a linear regression for the values of all fatty acid classes, y = 1.095 − 0.00665x, R = 0.869, P < 0.001.