Table 1.
Functional polymorphisms in key genes involved with chylomicron assembly
| Gene | Ref. SNP No. | Substitution | Reported Frequency | Observed Frequency | Effect on Postprandial Plasma TG | Reference No. |
|---|---|---|---|---|---|---|
| APOA4 | Rs675 | T347S | 0.20 | 0.30 | Decrease | 21,46 |
| APOB | Rs693 | 2488C>T | 0.47 | 0.52 | Decrease | 40 |
| APOB | rs679899 | V591A | 0.36 | 0.42 | Decrease | 54 |
| MTTP | rs1800591 | −493G>T | 0.25 | 0.23 | Increase | 43 |
| FABP2 | rs1799883 | A54T | 0.28 | 0.34 | Increase | 2 |
APO, apolipoprotein; MTTP, microsomal triglyceride transfer protein; FABP2, fatty acid-binding protein-2.