Fig. 6.

A–I: comparison of kinetics of lung monocytic phagocytes between wild-type and CCR2-deficient mice with experimental Gram-negative pneumonia. Cells enumerated in whole lung suspensions, identified as noted in Fig. 3, are shown at various times after intrapulmonary challenge with Klebsiella. Day 0 represents uninfected mice. *P < 0.05 comparing trend between the 2 groups over time (2-way ANOVA). Data shown represent means ± SE of representative data from 3 experiments; n = 4–5 for each group at each time point. iNOS, inducible nitric oxide synthase.