Table 1.
Mast cell degranulation in samples from the lungs of allergic rats, either ovariectomized (OVx) or sham-operated (Sham-OVx), that were subjected or not to formaldehyde (FA) inhalation (1%, 90 min daily, 3 days). A naïve group was used as the control. In a parallel set, the rats were treated with progesterone before the FA inhalation. The data are the mean ± SEM of 5 rats per group.
Mast cell number/mm2 | |||
Groups | Intact | Degranulated | % |
Naive | 2.15±0.03 | 0.04±0.04 | 0.0 |
OVA/OVA Sham-OVx | 0.36±0.06*) | 1.72±0.07*) | 82.5*) |
OVA/OVA OVx | 1.40±0.07*)# | 0.79±0.06*)# | 36.1*)# |
FA/OVA Sham-OVx | 1.62±0.04*)# | 0.12±0.03*)# | 26.5*)# |
FA/OVA OVx | 1.60±0.07*)θ | 0.30±0.07*)θ | 17.2*)θ |
FA/OVA OVx + P | 1.10±0.03*)θγ | 1.10±.0.20*)θγ | 50.0*)θγ |
p<0.05 vs. Naïve group; #p<0.05 vs. OVA/OVA Sham-OVx group; θ p<0.05 vs. FA/OVA Sham-OVx group; γ p<0.05 vs. FA/OVA OVx group.