Table A3A.
Summary of the PCV7 serotype-specific IgG responses ≥1.0 μg/ml following adjustment for eczema and atopy.
Adjusted |
||||
---|---|---|---|---|
Vaccine | Unadjusteda | IgE-eczema (at 12 months) | IgE-eczema (ever) | Atopy |
PCV7–4 | 1.30 (0.31, 5.40); p = 0.718 | 1.30 (0.30, 5.64); p = 0.726 | 1.28 (0.31, 5.36); p = 0.731 | 1.50 (0.34, 6.65); p = 0.591 |
PCV7–6B | 2.32 (0.72, 7.41); p = 0.157 | 2.21 (0.67, 7.27); p = 0.193 | 2.32 (0.72, 7.41); p = 0.157 | 2.24 (0.68, 7.40); p = 0.187 |
PCV7–9V | 1.22 (0.36, 4.17); p = 0.754 | 1.23 (0.35, 4.36); p = 0.752 | 1.20 (0.35, 4.14); p = 0.776 | 1.66 (0.44, 6.25); p = 0.456 |
PCV7–14 | 1.25 (0.34, 4.64); p = 0.739 | 1.20 (0.31, 4.63); p = 0.794 | 1.24 (0.33, 4.62); p = 0.746 | 1.25 (0.32, 4.82); p = 0.751 |
PCV7–18C | 1.56 (0.24, 10.05); p = 0.643 | NA | NA | NA |
PCV7–19F | 2.62 (0.92, 7.46); p = 0.072 | 2.32 (0.79, 6.79); p = 0.125 | 2.61 (0.92, 7.45); p = 0.073 | 2.49 (0.85, 7.32); p = 0.096 |
PCV7–23F | 2.00 (0.62, 6.46); p = 0.247 | 2.16 (0.64, 7.32); p = 0.217 | 1.98 (0.61, 6.47); p = 0.256 | 2.19 (0.64, 7.43); p = 0.210 |
Data represents the Odds Ratio and 95% confidence intervals; NA, not assessed due to co-linearity issues.
a Unadjusted analysis after removing missing data for eczema and atopy variables (N = 30 LGG; N = 30 Placebo).