FIG. 6.
Trophic support of resting and primed human SCs on different immune effectors. Resting and primed SCs were cocultured with unstimulated human IECs (ie, T, B, and NK cells). At the end of coculture, immune cell survival was detected by measuring cytosolic active-caspase-3 (as reported in Materials and Methods section). The results are expressed as percentage of caspase-3negCD45pos cells, and the analysis was performed by flow cytometry. Error bars represented mean±SD of five independent experiments for BM-MSCs, OE-MSCs, LeSCs, and AFSCs and three independent experiments for CSCs and LSCs. *P<0.05, **P<0.01, ***P<0.001.