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. 2013 Oct 1;5(11):1662–1683. doi: 10.1002/emmm.201202055

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© 2013 The Authors. Published by John Wiley and Sons, Ltd on behalf of EMBO

Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.

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Expression of p53-interating acetylases in the control, serum-deprived (SD), and oxygenated (SD + Oxy) H9c2, H9c2 p53^−/−, H9c2 p53-Lys¹¹⁸(Mut) cells, as determined by in vivo ELISA.

Expression of p53-interating acetylases in the control, serum-deprived (SD), and oxygenated (SD + Oxy) RNC, RNC p53^-/-, RNC p53-Lys¹¹⁸(Mut) cells. The results show that the expression of TIP60, a p53-interacting acetylase, is inhibited upon oxygenation in these cells.

Inhibition of TIP60 expression is also observed in the MI + OxCy heart tissues. Data represent mean ± SD of eight independent measurements in all groups. *p = 6.2E−12 versus respective MI group.