Table 2.
| Diet | Duration (wks) | Respiratory Substrates/Conditions
|
|||||||
|---|---|---|---|---|---|---|---|---|---|
| P/M | P/MADP | P/M/G/SADP | P/M/G/SADP + Rot | RCR | PC/M | PC/MADP | RCR | ||
| Std Chow | 3 | 190.5 ± 13.6 | 819.1 ± 70.3 | 1437 ± 122.5 | 947.5 ± 72.1 | 5.0 ± 0.5 | 127 ± 19.1 | 506.3 ± 67.6 | 3.8 ± 0.3 |
| n-3 PUFA | 3 | 215.7 ± 11.6 | 1097 ± 123.9 | 2044 ± 271.8 | 1546 ± 169.6 | 5.1 ± 0.3 | 153 ± 19.5 | 611.7 ± 82.3 | 4.1 ± 0.5 |
|
| |||||||||
| Std Chow | 14 | 240.2 ± 36.7 | 1302 ± 200.7 | 1671 ± 259.3 | 969.4 ± 119.2 | 5.4 ± 0.5 | 164.6 ± 19.9 | 625.3 ± 93.6 | 3.6 ± 0.6 |
| n-3 PUFA | 14 | 347.6 ± 63.3 | 2248 ± 530.8 | 3301 ± 736.3 | 1832 ± 337.7 | 6.3 ± 0.6 | 205.5 ± 39.6 | 606.4 ± 103.9 | 3.1 ± 0.3 |
| HFC | 14 | 402.5 ± 152.6 | 2537 ± 732.8 | 3134 ± 759.8 | 1966 ± 444.2 | 6.2 ± 0.7 | 261.2 ± 57.2 | 856.9 ± 168.7 | 3.3 ± 0.4 |
Data shown are mean ± S.E.M. in N = 7 for 3 week n-3 PUFA diet and N = 5 for 14 week n-3 PUFA diet. High Fat Control diet (HFC). Rates of respiration are in presence of 5 mM pyruvate/2 mM malate (P/M); P/M + 5 mM ADP (P/MADP); P/MADP + 5 mM glutamate, 5 mM succinate (P/M/G/SADP); P/M/G/SADP + 1 μM Rotenone (P/M/G/SADP + Rot); 100 μM palmitoyl-L-carnitine/2 mM malate (PC/M); PC/M + 5 mM ADP (PC/MADP); Respiratory Control Ratio (RCR)