Table 3.
Structural abnormalities for T18 and T13 cohorts who nderwent detailed anomaly scans
| Trisomy 18 (N = 17) | Trisomy 13 (N = 6) | |
|---|---|---|
|
Cardiac |
|
|
| Ventricular septal defect |
11 |
1 |
| Transposition of Great Arteries |
1 |
0 |
| Patent ductus arteriosus |
0 |
1 |
|
Cerebral |
|
|
| Holoprosencephaly |
0 |
2 |
| Cerebral ventriculomegaly |
2 |
0 |
| Microcephaly |
1 |
1 |
| Dandy Walker variant |
1 |
1 |
|
Structural |
|
|
| Cleft lip/palate |
2 |
4 |
| Talipes/rockerbottom feet |
5 |
2 |
| Clenched hands |
5 |
1 |
| Polydactyly |
0 |
1 |
| Low set ears |
1 |
0 |
| Short long bones |
3 |
0 |
| Overlapping fingers |
0 |
1 |
| Micrognathia |
2 |
0 |
| Ocular hypotelorism |
1 |
1 |
| Syndactyly |
2 |
0 |
|
Gastrointestinal |
|
|
| Small/absent stomach |
3 |
1 |
| Omphalocele |
4 |
0 |
| Umbilical herniation |
1 |
0 |
|
Respiratory |
|
|
| Pleural effusion |
1 |
0 |
| Diaphragmatic hernia |
3 |
0 |
|
Renal |
|
|
| Enlarged/cystic kidneys | 1 | 3 |
Structural abnormalities for T18 and T13 cohorts who underwent detailed anomaly scans.