Table 1.
Cytokine mRNA expression index from ear biopsies
| Vehicle | TPA | TPA w. scrambled | TPA w. CKS-17 | p-value | |
|---|---|---|---|---|---|
|
IL-1a |
1(0.77–1.22) |
3.64(2.76–5.55) |
2.82(1.97–4.31) |
2.1(1.21–3.67) |
0.143 |
|
IL-6 |
1(0.81–1.19) |
39.3(13.4–73.5) |
217(12.9–976) |
4.23(1.82–6.39) |
0.068 |
|
IL-10 |
1(0.95–1.04) |
5.63(3.49–9.16) |
8.75(4.01–18.47) |
3.61(1.00–5.49) |
0.071 |
|
IL-17c |
1(0.54–1.46) |
4.17(1.04–7.54) |
3.34(0.81–8.12) |
0.85(0.24–1.54) |
0.744 |
|
TNF-α |
1(0.49–1.51) |
3.93(0.56–10.1) |
7.27(0.48–25.3) |
0.3(0.17–0.52) |
0.040 |
| CXCL2 | 1(0.41–1.59) | 1162(402–2846) | 7339(12.3–29363) | 86(6.7–358) | 0.432 |