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. 2013 Nov 13;14:250. doi: 10.1186/1471-2369-14-250

Table 2.

Comparison, correlation, bias and precision between measured 8-hr CLCR and mathematical estimates in all patients, and each diagnostic sub-group

  Mean (SD) r ( P -value) Bias +/− precision
All patients (n = 110)
CLCR, ml/min/1.73 m2
 125 (45.1)
  
  
175 eGFR, ml/min/1.73 m2
 110 (41.6)*
 0.600 (<0.001)
 15.6 +/− 38.9
CG CLCR, ml/min/1.73 m2
 119 (41.7)
 0.638 (<0.001)
 6.23 +/− 37.1
CKD-EPI eGFR, ml/min/1.73 m2
 101 (23.7)*
 0.720 (<0.001)
 24.4 +/− 32.5
Elective admissions (n = 15)
CLCR, ml/min/1.73 m2
 118 (27.2)
  
  
175 eGFR, ml/min/1.73 m2
 115 (51.2)
 0.325 (0.237)
 2.77 +/− 49.5
CG CLCR, ml/min/1.73 m2
 119 (44.1)
 0.531 (0.042)
 −1.04 +/− 37.5
CKD-EPI eGFR, ml/min/1.73 m2
 101 (20.0)**
 0.488 (0.065)
 17.2 +/− 24.7
Emergency admission (n = 33)
CLCR, ml/min/1.73 m2
 113 (50.0)
  
  
175 eGFR, ml/min/1.73 m2
 114 (47.9)
 0.624 (<0.001)
 −0.77 +/− 42.5
CG CLCR, ml/min/1.73 m2
 123 (49.1)
 0.599 (<0.001)
 −10.4 +/− 44.3
CKD-EPI eGFR, ml/min/1.73 m2
 99 (27.6)**
 0.692 (<0.001)
 13.8 +/− 36.8
Surgical emergency admission (n = 37)
CLCR, ml/min/1.73 m2
 125 (46.4)
  
  
175 eGFR, ml/min/1.73 m2
 101 (37.2)*
 0.741 (<0.001)
 23.7 +/− 31.3
CG CLCR, ml/min/1.73 m2
 108 (37.5)**
 0.753 (<0.001)
 16.4 +/− 30.6
CKD-EPI eGFR, ml/min/1.73 m2
 95 (23.7)*
 0.779 (<0.001)
 29.5 +/− 31.6
Trauma admission (n = 25)
CLCR, ml/min/1.73 m2
 146 (39.5)
  
  
175 eGFR, ml/min/1.73 m2
 114 (32.0)*
 0.745 (<0.001)
 32.7 +/− 26.5
CG CLCR, ml/min/1.73 m2
 129 (33.8)**
 0.757 (<0.001)
 17.4 +/− 26.1
CKD-EPI eGFR, ml/min/1.73 m2 111 (17.4)* 0.772 (<0.001) 35.2 +/− 28.4

* P < 0.001, when compared to CLCR ** P < 0.05, when compared to CLCR.

CLCR = 8-hr Creatinine Clearance, CG CLCR = Cockcroft-Gault Creatinine Clearance, 175 eGFR = Abbreviated Modification of Diet in Renal Disease 175 formula, CKD-EPI eGFR = Chronic Kidney Disease Epidemiology Collaboration Equation, r = Pearson correlation coefficient.