Table 3.
Author(s) | Species | Etiology | Deafness onset | Change(s) observed |
---|---|---|---|---|
Moore and Kowalchuk, 1988 | Ferret | Cochlear lesion | Day 12–93 | ↓ volume |
Nishiyama et al., 2000 | Cat | Ototoxic | Day 10 | ↓ soma area |
Hardie et al., 1998 | Cat | Ototoxic | Day 10 | ↓ synaptic density |
↓ # of presynaptic vesicles | ||||
Trune, 1983 | Mouse | Cochlear lesion | Day 6 | ↓ # of projections from CN |
Vale and Sanes, 2000 | Gerbil | Cochlear ablation | Day 7 | ↓ inhibitory synapse strength |
Vale and Sanes, 2002 | Gerbil | Cochlear ablation | Day 9 | ↓ inhibitory and excitatory synapse strength |
Shepherd et al., 1999 | Cat | Ototoxic | Day 10 | ↓ temporal resolution |
Snyder et al., 1995 | Cat | Ototoxic | Day 16 | ↓ temporal resolution |
Vollmer et al., 2005 | Cat | Ototoxic | Day 14–25 | ↓ temporal resolution |
Moore, 1994 | Ferret | Cochlear removal | Day 25 | No change in # of neurons |
Moore, 1990 | Ferret | Cochlear removal | Day 5 | No change in # of neurons |
No change in projection pattern from CN | ||||
Russell and Moore, 1995 | Gerbil | Cochlear removal | Day 2–14 | No change in projection pattern from SO |
Heid et al., 1997 | Cat | Congenital | Day 0 | No change in projection pattern from CN/SO |
Tonotopy is maintained | ||||
Shepherd and Javel, 1999 | Cat | Ototoxic | Unknown | Tonotopy is maintained |
Snyder et al., 1990 | Cat | Ototoxic | Day 16 | Tonotopy is maintained |
Snyder et al., 1991 | Cat | Ototoxic | Day 16 | Tonotopy is maintained |
CN, Cochlear nucleus; SO, Superior olive.