Table 3.

Global gray matter and white matter volumes in the study participants^*

	Gray matter	White matter
Controls (n =19)	600.7 ± 66.2	422.3 ± 39.7
All patients with childhood-onset SLE (n =22)	569.1 ± 101.9	406.8 ± 50.7
Patients with childhood-onset SLE with normal cognition (n =14)	597.4 ± 68.2	423.0 ± 42.7
Patients with childhood-onset SLE with neurocognitive deficit (n =8)	519.5 ± 40.4	378.3 ± 53.4
P
Controls versus all patients with childhood-onset SLE	0.15	0.28
Controls versus patients with childhood-onset SLE with normal cognition	0.89	0.96
Controls versus patients with childhood-onset SLE with neurocognitive deficit	0.00082	0.061
Patients with childhood-onset SLE with normal cognition versus patients with childhood-onset SLE with neurocognitive deficit	0.0031	0.065

^*Values are the mean ± SD cm³. SLE = systemic lupus erythematosus.