Table 1.

Body mass, food intake and tissue masses in young and old normal chow (NC) and western diet (WD) fed cage control and voluntary running (VR) mice.

	Y NC	O NC	Y WD	O WD	Y WD-VR	O WD-VR
N	9	8	9	8	6	6
Body Mass (g)	32.8 ± 0.7	34.4 ± 0.6	36.3 ± 1.5	40.4 ± 2.5*†	29.0 ± 0.8‡	30.7 ± 1.3‡
Food Intake (kcal/day)	14.6 ± 0.3	15.1 ± 0.2	14.1 ± 0.2	15.2 ± 0.9	16.0 ± 0.7	15.8 ± 0.9
Food Intake (g/day)	4.9 ± 0.1	5.0 ± 0.1	3.1 ± 0.1*	3.4 ± 0.2*†	3.6 ± 0.1	3.5 ± 0.2
Heart Mass (g)	0.19 ± 0.01	0.23 ± 0.01*	0.17 ± 0.01	0.21 ± 0.01	0.17 ± 0.01	0.26 ± 0.03§
Heart:Body Mass (%)	0.54 ± 0.03	0.66 ± 0.03*	0.57 ± 0.04	0.57 ± 0.04†	0.58 ± 0.04	0.84 ± 0.10‡†
Liver Mass (g)	1.9 ± 0.1	2.1 ± 0.2	1.7 ± 0.1	2.1 ± 0.1	1.5 ± 0.1	2.1 ± 0.2
Liver:Body Mass (%)	5.4 ± 0.2	5.4 ± 0.2	4.8 ± 0.2	5.8 ± 0.4	5.2 ± 0.2	6.4 ± 0.5§
WAT Mass (g)	1.1 ± 0.2	0.6 ± 0.1	1.6 ± 0.2	1.9 ± 0.5*†	0.7 ± 0.1‡	0.4 ± 0.1‡§
WAT:Body Mass (%)	2.9 ± 0.4	1.7 ± 0.2	4.5 ± 0.3*	4.7 ± 1.1*†	2.6 ± 0.3‡	1.4 ± 0.2‡§
Gast Mass (g)	0.19 ± 0.01	0.15 ± 0.01*	0.19 ± 0.01	0.15 ± 0.01*	0.18 ± 0.01	0.14 ± 0.01§
Gast:Body Mass (%)	0.56 ± 0.04	0.43 ± 0.02*	0.53 ± 0.03	0.37 ± 0.02*	0.63 ± 0.03‡	0.41 ± 0.07§

Y: young; O: old; NC: normal chow; WD: western diet; WAT: epididymal white adipose tissue, Gast: gastrocnemius muscle;

^*Denotes difference from Y NC,

^†denotes difference from O NC.

^‡denotes difference from age-matched cage-control WD fed mice;

^§denotes difference from YWD-VR, Data presented as mean ± SEM, P<0.05