Table 2.
Results of Immunohistochemical Scoring and Statistical Comparison of Individual Groups According to Proteins.
|
p Value |
||||||||
|---|---|---|---|---|---|---|---|---|
| Median | IQR | K-W Test | vs. COL | vs. SQU BAS | vs. SQU PAR | vs. CIN | ||
| Claudin 1 | RC | 9 | 2.25 | <0.001* | <0.0001* | <0.0001* | <0.0001* | 1.0000 |
| COL | 0 | 0.00 | 1.0000 | <0.0001* | <0.0001* | |||
| SQU BAS | 0 | 0.00 | <0.0001* | <0.0001* | ||||
| SQU PAR | 4 | 2.50 | <0.0001* | |||||
| CIN | 9 | 3.00 | ||||||
| Claudin 2 | RC | 4 | 3.00 | <0.001* | 1.0000 | 1.0000 | <0.0001* | 1.0000 |
| COL | 4 | 2.00 | 0.8372 | <0.0001* | 1.0000 | |||
| SQU BAS | 4 | 1.00 | <0.0001* | 1.0000 | ||||
| SQU PAR | 2 | 1.00 | <0.0001* | |||||
| CIN | 4 | 2.50 | ||||||
| Claudin 4 | RC | 2 | 2.00 | 0.0488 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
| COL | 2 | 1.75 | 1.0000 | 1.0000 | 1.0000 | |||
| SQU BAS | 1 | 3.00 | 1.0000 | 0.0622 | ||||
| SQU PAR | 1.5 | 2.00 | 0.1681 | |||||
| CIN | 2.5 | 1.75 | ||||||
| Claudin 7 | RC | 4 | 2.00 | <0.001* | <0.0001* | <0.0001* | 0.0765 | 1.0000 |
| COL | 1 | 0.75 | 0.0012* | 0.0043* | <0.0001* | |||
| SQU BAS | 0 | 0.00 | <0.0001* | <0.0001* | ||||
| SQU PAR | 2 | 2.75 | 0.0714 | |||||
| CIN | 4 | 1.75 | ||||||
| Occludin | RC | 6 | 2.00 | <0.001* | <0.0001* | 0.1309 | <0.0001* | 1.0000 |
| COL | 0 | 0.00 | <0.0001* | <0.0001* | <0.0001* | |||
| SQU BAS | 4 | 3.00 | 0.0001* | 0.1439 | ||||
| SQU PAR | 2 | 1.00 | <0.0001* | |||||
| CIN | 6 | 1.50 | ||||||
Median and interquartile range values of immunohistochemical scoring are listed. Statistical comparison of horizontal versus vertical groups was performed using the Kruskal-Wallis test. Significant differences (p<0.05) are marked by asterisks. IQR, interquartile range (3 quartile–1 quartile); K-W Test, Kruskal-Wallis test; RC, reserve cell; COL, columnar glandular cell; SQU BAS, squamous basal cell; SQU PAR, squamous parabasal cell; CIN, cervical intraepithelial neoplasia.