Figure 2.

Relationship between urinary isoprostane level and glucose excursion (GE).

Notes: Urinary isoprostane levels were grouped according to tertile of GE. Data are expressed according to glucose-tolerance test diagnosis. Bars indicate standard error. Mean GE levels among normal glucose tolerance (NGT) subjects, from lowest to highest tertile, were 1.32±0.57, 3.01±0.46, and 5.21±1.10 mmol/L, respectively. Among the impaired glucose tolerance (IGT) subjects, these levels were 3.89±0.65, 5.46±0.39, and 7.17±0.81 mmol/L, respectively. Among the subjects with diabetes mellitus (DM), these levels were 6.81±0.91, 8.38±0.33, and 10.54±1.51 mmol/L, respectively. Numbers of subjects according to GE tertile were 184, 191, and 183 for the NGT group, 54, 52, and 59 for the IGT group, and 19, 17, and 16 for the DM group. Trend analysis revealed P=0.002, P=0.350, and P=0.044 among NGT, IGT, and subjects with diabetes, respectively. *P<0.05 compared with the lowest tertile by the Tukey–Kramer method.

Abbreviation: Cr, creatinine.