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. 2013 Aug 30;14(4):1321–1332. doi: 10.1208/s12249-013-0014-6

Table VII.

Comparison of Optimized Porous (F4) and Nonporous (NF4) Film of Glibenclamide

Parameters Porous film (F4) Nonporous film (NF4)
Swelling index after 120 min 51.26 ± 0.70 35.71 ± 0.70
Mucoadhesion time (min) 539.11 ± 3.05 510.00 ± 2.00
Mucoadhesive force (N) 0.24 ± 0.04 0.20 ± 0.05
% Cumulative drug release at 8 h 84.47 ± 0.94 62.66 ± 0.87
% Cumulative drug permeated at 8 h 68.33 ± 0.67 53.47 ± 0.78
Release kinetics Zero order Peppas
Correlation between in vitro drug release and ex vivo drug permeation (r 2) 0.9931 0.9846