Table 2.

Multivariable Adjusted Associations between BNP Assessments and Time to Heart Failure Hospitalization or Heart Failure Mortality after Primary Coronary Artery Bypass Graft Surgery^*

Perioperative BNP Variable; n = 947†; 99 Subjects with Heart Failure Events	Hazard Ratio (95% CI)	P Value	AIC of Multivariable Model* with BNP Included in Model
Preoperative BNP (pg/ml)	1.93 (1.30–2.88) for log10 increase	0.001	1,185.25
Peak postoperative BNP (pg/ml)	3.38 (1.45–7.65) for log10 increase	0.003	1,190.24
Preoperative BNP (pg/ml) together with	1.67 (1.09–2.56) for log10 increase	0.02	1,185.28
Peak postoperative BNP (pg/ml)	1.96 (0.77–4.98) for log10 increase	0.16

^*Variables in multivariable clinical model are shown in Supplemental Digital Content 1, table 1, http://links.lww.com/ALN/A945. The AIC of the Supplemental Digital Content 1, table 1 model = 1,196.90 before adding BNP data to the model.

^†Seventy-eight subjects missing one or more of the variables in Supplemental Digital Content 1, table 1, http://links.lww.com/ALN/A945, are not included in the multivariable analysis.

AIC = Akaike information criterion; BNP = B-type natriuretic peptide.