Table 1.

Comparison of published cases of olanzapine-induced hypothermia in the English literature.

Case	Age/sex	Diagnosis	Baseline daily olanzapine dosage	Duration of stable olanzapine dosage	Dose of olanzapine prior to hypothermia	Comedications	Time to development of hypothermia after dose initiation or change	Duration of hypothermia after olanzapine	Lowest temperature in degrees Celsius	Renal function
Kreuzer et al. 2012b	51 F	Catatonic schizophrenia	30 mg	2 weeks	30 mg	Lorazepam	Few hours	Not reported	30.0	Not reported
Kreuzer et al. 2012b	48 F	Schizophrenia	Haloperidol 5 mg	6 months	10 mg	Lorazepam	Not reported	Not reported	31.0	Not reported
Kreuzer et al. 2012b	69 M	Acute delusional disorder	None	None	10 mg	None	Not reported	Not reported	33.0	Not reported
Rasnayake et al. 2011	42 M	Schizophrenia	10 mg	6 years	10 mg	Not reported	Not reported	24 h	32.0	Normal, creatinine not reported
Hung et al. 2009	17 M	Schizophreniform disorder	10 mg	1 day	5 mg intramuscularly × 1	Clonazepam	2 h	2 h	34.9	Normal, creatinine not reported
Blass and Chuen,2004	64 F	Bipolar disorder	2.5 mg	Not reported	5 mg every morning, 6.5 mg every evening	Gabapentin	7 days	24 h	33.4	Normal, creatinine 1.2
Fukunishi 20037	54 M	Acute delirium	2.5 mg	21 days	2.5 mg	None	2 days	6 days	33.0	End-stage renal disease on hemodialysis
Hagg et al. 2001	73 M	Schizophrenia	None	None	10 mg	None	4 h	36 h	31.7	Abnormal for system, creatinine 1.35
Parris et al. 2001	83 F	Bipolar disorder	5 mg	3 weeks	5 mg	Lithium carbonate, clonazepam and trazodone	Not reported	24 h	33.1	Normal, creatinine 1.0
Phan et al. 1998	37 F	Prader–Willi and psychosis	None	None	Not reported	Prednisone, flucloxacillin	Not reported	Not reported	34	Not reported