Table III.
Ratio of T-cell and NK cell to monoclonal B cell at diagnosis
| Prognostic factors/variable | Number of patients |
Median ratio absolute NK/absolute monoclonal B |
Median ratio absolute T/absolute monoclonal B |
||
|---|---|---|---|---|---|
| All patients | 166 | 0.07 | 0.26 | ||
|
| |||||
| Rai Stage at diagnosis | p<0.0001 | p=0.0003 | |||
| 0 | 113 | 0.09 | 0.28 | ||
| I/II | 40 | 0.04 | 0.13 | ||
| III/IV | 8 | 0.01 | 0.06 | ||
|
| |||||
| CD38 | p=0.49 | p=0.58 | |||
| Positive (≥30%) | 54 | 0.07 | 0.27 | ||
| Negative (<30%) | 107 | 0.07 | 0.23 | ||
|
| |||||
| ZAP-70 | p=0.24 | p=0.77 | |||
| Positive (≥20%) | 12 | 0.04 | 0.23 | ||
| Negative (<20%) | 34 | 0.05 | 0.22 | ||
|
| |||||
| IgVH gene mutation status | p=0.0002 | p=0.0002 | |||
| Unmutated | |||||
| Mutated | 27 | 0.02 | 0.08 | ||
| 41 | 0.10 | 0.23 | |||
|
| |||||
| FISH result | p=0.66 | p=0.53 | |||
| 13q- | 26 | 0.05 | 0.19 | ||
| Normal | 18 | 0.04 | 0.12 | ||
| +12 | 15 | 0.04 | 0.22 | ||
| 11q-/17p- | 11 | 0.04 | 0.19 | ||