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Active lever presses (right abscissa) and METH intake (left abscissa) in the extended-access (n = 15) and limited-access (n = 12) groups. During the first hour, beginning in session 8, the extended-access group exhibited a significant increase in METH intake compared with the limited-access group (*P < 0.05). White symbols represent the microdialysis days. The data are expressed as mean ± SEM.
