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. 2013 Oct 24;1(5):e00133. doi: 10.1002/phy2.133

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© 2013 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society

Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.

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Finasteride does not alter NMDAR EPSPs. (A) In the presence of CNQX and low magnesium administration of 1 μmol/L finasteride (filled bar) has no effect on NMDAR EPSPs in the SC pathway elicited by a single puse. Traces show baseline EPSPs (red dashed top traces) with solid traces at the end of finasteride administration. (B) NMDAR-mediated EPSP areas were measured before and 30 min after administration of 1 μmol/L finasteride. NMDAR-mediated EPSPs were elicited by single pulse or by trains of six pulses at 100 Hz (open bars in histogram and solid traces are before and red bars and red dotted traces are 30 min after finasteride administration).