Figure 3. Super-enhancers and candidate master transcription factors in many cell types.
A) Heatmap showing the classification of super-enhancer domains across 26 human cell and tissue types. Color scale reflects the density of H3K27ac signal at the super-enhancer regions.
B) Gene Ontology terms for super-enhancer-associated genes in 13 human cell and tissue types with corresponding p-values.
C) Candidate master transcription factors identified in 6 cell types. All of these transcription factors were previously demonstrated to play key roles in the biology of the respective cell type or facilitate reprogramming to the respective cell type.
See also Figure S3.