Figure 4.

hCNS-SCns transplantation at 9 or 60 DPI does not alter CGRP fiber volume or sprouting in dorsal horn laminae III–IV. An example of coronal spinal cord section after immunohistochemistry using CGRP-specific antibody is shown (A). Scale bars = 500 μm (left) and 50 μm (right). CGRP fiber volume and length are shown in the 9 DPI vehicle and transplant groups (B) and the 60 DPI vehicle and transplant groups (C). No significant differences were found between the groups (Student's t test; p > .5). Error bars indicate SEM. Data were previously published in [7]. Abbreviations: CGRP, calcitonin gene-related peptide; DPI, days postinjury; hCNS-SCns, human central nervous system-derived neural stem cell; NS, not significant.